CJC-1295 with DAC (Drug Affinity Complex) is a synthetic analogue of growth hormone-releasing hormone (GHRH) modified with a maleimidopropionic acid linker that binds to serum albumin. This modification extends the peptide’s half-life significantly compared to the No DAC variant, making it an essential compound for researchers studying sustained growth hormone axis stimulation in laboratory models.
Growth Hormone Axis Research
The DAC modification enables prolonged GHRH receptor activation, providing researchers with a unique tool for studying extended-release kinetics. CJC-1295 with DAC is frequently explored for:
– Sustained GH Secretion: Investigating how prolonged GHRH receptor agonism affects pulsatile growth hormone release patterns over extended periods.
– Albumin Binding Kinetics: Studying the pharmacokinetic properties of DAC-modified peptides and their extended circulation time in biological models.
– IGF-1 Pathway Activation: Researching downstream effects on insulin-like growth factor signalling cascades in response to sustained GH elevation.
Mechanisms and Comparative Studies
CJC-1295 with DAC offers researchers a pharmacologically distinct profile from the No DAC variant, enabling comparative studies across:
– Half-Life Extension: Comparing the biological activity window of DAC-modified versus unmodified GHRH analogues.
– Receptor Desensitisation: Investigating whether sustained receptor occupancy leads to tachyphylaxis or maintained signalling efficacy.
– Somatotroph Biology: Exploring pituitary somatotroph cell responses to continuous versus pulsatile GHRH stimulation in vitro.
The CJC-1295 with DAC Pen: Precision for Laboratory Studies
Our CJC-1295 with DAC Pen delivery system is engineered to provide researchers with the ultimate tool for precise administration. Moving beyond traditional lyophilized vials, the pre-filled pen format ensures:
– Exact Dosing: Dial-in mechanisms allow for milligram-precise measurements, crucial for maintaining consistency in research protocols.
– Peptide Integrity: The airtight, light-resistant housing protects the peptide structure from environmental degradation and UV exposure.
– Streamlined Workflow: No manual syringe drawing or complex measuring is required, reducing the risk of contamination and human error.
– Stability: The pre-filled pen format is designed to maintain the peptide’s stability throughout use.
Disclaimer: This product is intended for laboratory and scientific research purposes only. CJC-1295 with DAC is not for human or animal consumption. It is not a drug, food, or cosmetic. Please ensure compliance with local regulations and laboratory safety protocols before purchase.















Reviews
There are no reviews yet.